C-JUN 抗体
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北京 101111
Quick Overview for C-JUN 抗体 (ABIN272013)
抗原
See all C-JUN (JUN) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of c-Jun protein. (region surrounding Ile245)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (pThr91) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Jun Proto-Oncogene (JUN) (pSer73) antibodyJUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (N-Term) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyKD Validated JUN 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB5760 unconjugated
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应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- DO NOT FREEZE!
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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别名
- AP-1 / C-Jun
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背景
- Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1 originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA- response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, while Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. An inhibitor of Fos/Jun function, termed IP-1, associates with Fos and Jun and is inactivated upon phosphorylation induced by the cAMP-dependent protein kinase A (PKA).Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39
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分子量
- approx. 43, 48 kDa
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基因ID
- 3725
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NCBI登录号
- NP_002219
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UniProt
- P05412
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途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
抗原
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