(4 references)-
- 抗原 See all TNFRSF4 抗体
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF4 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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The OX-40 antibody reacts with the 50- kDa OX-40 Antigen (CD134), also known as OX-40 Receptor, on CD4+ T lymphocytes activated in vitro and in vivo. The antigen is a member of the NGFR/TNFR superfamily, which includes low-affinity nerve growth factor receptor, TNF receptors, the Fas antigen, CD137 (4-1BB), CD27, CD30, and CD40. CD134 supplies costimulatory signals for T-cell proliferation and effector functions. While OX-40 mAb is not mitogenic, it does augment some in vitro T-cell responses. It is also reported to block binding of OX-40 Ligand to OX-40 Antigen.
BD Pharmingen™ Biotin Mouse Anti-Rat CD134 - Biotin - Clone OX-40 - Isotype Mouse IgG2b, κ - Reactivity Rat - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Activated rat lymph node cells
- 克隆位点
- OX
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TNFRSF4 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 59-205) antibody
TNFRSF4 适用: 人, Chimpanzee FACS, ELISA, IHC, IF, Coat, ISt, StM 宿主: 小鼠 Monoclonal OX40-3108 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibodyTNFRSF4 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 3G5G7 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (PE)TNFRSF4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal Ber-ACT35 PE
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (FITC)TNFRSF4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal Ber-ACT35 FITC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibody (APC)TNFRSF4 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal Ber-ACT35 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-214) antibodyTNFRSF4 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 2D1B8 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 101-200) antibodyTNFRSF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (fro), IF (cc), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 29-216) antibodyTNFRSF4 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM116 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) antibodyTNFRSF4 适用: 人, Non-Human Primate WB, FACS, ELISA, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal Ber-ACT35 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4) (AA 100-200) antibodyTNFRSF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "OX-40: life beyond the effector T cell stage." in: Seminars in immunology, Vol. 10, Issue 6, pp. 471-80, (1999) (PubMed).
: "OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand." in: European journal of immunology, Vol. 26, Issue 8, pp. 1695-9, (1996) (PubMed).
: "The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death." in: Cell, Vol. 76, Issue 6, pp. 959-62, (1994) (PubMed).
: "Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes--a molecule related to nerve growth factor receptor." in: The EMBO journal, Vol. 9, Issue 4, pp. 1063-8, (1990) (PubMed).
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: "OX-40: life beyond the effector T cell stage." in: Seminars in immunology, Vol. 10, Issue 6, pp. 471-80, (1999) (PubMed).
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- 抗原
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- 别名
- CD134 (TNFRSF4 产品)
- 别名
- TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
- 背景
- Synonyms: OX-40 Antigen
- 途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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