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TNFRSF4 抗体 (AA 59-205)

TNFRSF4 适用: 人, Chimpanzee FACS, ELISA, IHC, IF, Coat, ISt, StM 宿主: 小鼠 Monoclonal OX40-3108 unconjugated
产品编号 ABIN6940817
发货至: 中国
  • 抗原 See all TNFRSF4 抗体
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-205
    适用
    • 64
    • 49
    • 31
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    人, Chimpanzee
    宿主
    • 56
    • 30
    • 13
    • 2
    小鼠
    克隆类型
    • 53
    • 46
    单克隆
    标记
    • 51
    • 12
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF4 antibody is un-conjugated
    应用范围
    • 58
    • 44
    • 30
    • 14
    • 14
    • 13
    • 11
    • 10
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Coating (Coat), Immunostaining (ISt), Staining Methods (StM)
    特异性
    ThisMAb recognizes a protein of 43 kDa, identified as OX40, which is also known as CD134.OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand/TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells.OX40 is upregulated at the sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human OX40 (CD134) protein (around aa 59-205) (exact sequence is proprietary)
    克隆位点
    OX40-3108
    亚型
    IgG2c kappa
  • 应用备注

    Positive Control: MOLT-4 cells. Human peripheral blood leukocytes (hPBL). Human tonsil tissue (IHC).

    Known Application: ELISA (For coating, order antibody without BSA),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    别名
    TNFRSF4 (TNFRSF4 产品)
    别名
    TNFRSF4 antibody, ACT35 antibody, CD134 antibody, Ly-70 antibody, Ox40 antibody, TXGP1L antibody, Txgp1 antibody, OX40 antibody, TNF receptor superfamily member 4 antibody, tumor necrosis factor receptor superfamily, member 4 antibody, TNFRSF4 antibody, Tnfrsf4 antibody
    分子量
    43kDa
    基因ID
    7293
    UniProt
    P43489
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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