TNFRSF4 抗体 (AA 29-216)
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Quick Overview for TNFRSF4 抗体 (AA 29-216) (ABIN7092917)
抗原
See all TNFRSF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-216
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原理
- Anti-OX40 antibody(DM116), Rabbit mAb
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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免疫原
- Recombinant human OX40 (Leu29-Ala216) ((ABIN6961095, ABIN7042219 and ABIN7042220)) produced by using human HEK293 cells
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亚型
- IgG
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应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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别名
- OX40
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背景
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Synonyms:TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. -
分子量
- 47.2 kDa
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基因ID
- 7293
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UniProt
- P43489
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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