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Retinoblastoma 1 抗体 (AA 393-572)

RB1 适用: 人 IP 宿主: 小鼠 Monoclonal XZ104 unconjugated
产品编号 ABIN264372
发货至: 中国
  • 抗原 See all Retinoblastoma 1 (RB1) 抗体
    Retinoblastoma 1 (RB1)
    抗原表位
    • 32
    • 26
    • 26
    • 24
    • 23
    • 21
    • 19
    • 15
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 393-572
    适用
    • 270
    • 112
    • 95
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 247
    • 26
    小鼠
    克隆类型
    • 238
    • 35
    单克隆
    标记
    • 128
    • 19
    • 17
    • 16
    • 11
    • 10
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoblastoma 1 antibody is un-conjugated
    应用范围
    • 208
    • 121
    • 110
    • 80
    • 79
    • 40
    • 32
    • 28
    • 25
    • 19
    • 16
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    Immunoprecipitation (IP)
    特异性
    ,Species:Human, Chicken and Mouse.
    产品特性
    Synonyms: Retinoblastoma 1, Rb, p105-Rb, pRb, pp110, OSRC
    纯化方法
    From ascites.
    免疫原
    Recombinant protein corresponding to amino acids 393 to 572 of the humanretinoblastoma sequence.
    克隆位点
    XZ104
    亚型
    IgG1
    Top Product
    Discover our top product RB1 Primary Antibody
  • 应用备注
    Immunoprecipitation. This antibody is not recommended for Western blotting or Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.08 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    有效期
    12 months
  • 抗原
    Retinoblastoma 1 (RB1)
    别名
    Retinoblastoma-Associated Protein / RB1 (RB1 产品)
    别名
    OSRC antibody, RB antibody, p105-Rb antibody, pRb antibody, pp110 antibody, Rb antibody, Rb-1 antibody, P105-RB antibody, PP110 antibody, RB11 antibody, zgc:154147 antibody, RB transcriptional corepressor 1 antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma 1 antibody, RB1 antibody, RBL1 antibody, Rb1 antibody, rb1 antibody
    背景
    Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.Synonyms: OSRC, Rb, Retinoblastoma 1, p105-Rb, pRb, pp110
    基因ID
    5925
    UniProt
    P06400
    途径
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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