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PAK1 抗体 (pSer204)

PAK1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2568413
发货至: 中国
  • 抗原 See all PAK1 抗体
    PAK1 (P21-Activated Kinase 1 (PAK1))
    抗原表位
    • 34
    • 17
    • 15
    • 11
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    • 9
    • 7
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    • 3
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    • 1
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    pSer204
    适用
    • 167
    • 93
    • 81
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 160
    • 4
    • 1
    • 1
    克隆类型
    • 157
    • 10
    多克隆
    标记
    • 84
    • 10
    • 7
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    • 6
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    • 6
    • 6
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    This PAK1 antibody is un-conjugated
    应用范围
    • 112
    • 64
    • 45
    • 39
    • 39
    • 29
    • 28
    • 11
    • 10
    • 9
    • 8
    • 6
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    The antibody detects endogenous levels of PAK1 only when phosphorylated at serine 204.
    纯化方法
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    免疫原
    PAK1 (phospho Ser204) antibody was raised against a peptide sequence around phosphorylation site of Serine 204 (T-R-S (p)-V-I) derived from Human PAK1.
    亚型
    IgG
    Top Product
    Discover our top product PAK1 Primary Antibody
  • 应用备注
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store antibody at -20°C for up to one year.
  • 抗原
    PAK1 (P21-Activated Kinase 1 (PAK1))
    别名
    PAK1 (PAK1 产品)
    别名
    X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, PAKalpha antibody, AW045634 antibody, PAK-1 antibody, Paka antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, p21 protein (Cdc42/Rac)-activated kinase 1 antibody, Serine/threonine-protein kinase pak-1 antibody, pak1.S antibody, PAK1 antibody, Pak1 antibody, pak-1 antibody
    背景
    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
    分子量
    65 kDa
    基因ID
    5058
    NCBI登录号
    NP_002567
    UniProt
    Q13153
    途径
    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
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