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PAK1 抗体 (pThr212)

Name: PAK1 抗体 (pThr212)
Brand: antibodies-online
SKU: ABIN7138803
Availability: OutOfStock

PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts from 293 cells untreated or treated with forskolin using PAK1(Phospho-Thr212) Antibody. (PAK1 抗体 (pThr212))

Immunofluorescence staining of methanol-fixed Hela cells using PAK1(Phospho-Thr212) Antibody. (PAK1 抗体 (pThr212))

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using PAK1(Phospho-Thr212) Antibody(left) or the same antibody preincubated with blocking peptide(right). (PAK1 抗体 (pThr212))

IHC

3 images

产品编号 ABIN7138803

发货至: 中国

Datasheet as PDF

抗原 See all PAK1 抗体

PAK1 (P21-Activated Kinase 1 (PAK1))
抗原表位
33

17

15

13

10

10

9

9

8

7

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pThr212
适用
173

95

83

7

5

4

4

3

3

2

1

1
人
宿主
166

4

1

1
兔
Compatible Secondaries
克隆类型
160

13
多克隆
标记
90

10

7

7

6

6

6

6

6

6

4

4

3

3

3

3

3
This PAK1 antibody is un-conjugated
应用范围
116

65

44

39

39

34

31

14

11

10

10

6

4

3

3

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

交叉反应

人, 小鼠, 大鼠

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of threonine 212 (P-V-T(p)-P-T) derived from Human PAK1.

亚型

IgG

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anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibody
PAK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibody
PAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibody
PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Ser204) antibody
PAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Thr423) antibody
PAK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

PAK1 (P21-Activated Kinase 1 (PAK1))

别名

PAK1 (PAK1 产品)

别名

X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, PAKalpha antibody, AW045634 antibody, PAK-1 antibody, Paka antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, p21 protein (Cdc42/Rac)-activated kinase 1 antibody, Serine/threonine-protein kinase pak-1 antibody, pak1.S antibody, PAK1 antibody, Pak1 antibody, pak-1 antibody

背景

Background: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Alexander K, et al. (2004) Mol Cell Biol, 24: 2808-2819
Thiel DA, et al. (2002) Curr Biol, 12:1227-1232
Rashid T, et al. (2001) J. Biol. Chem, 276: 49043 - 49052.
Aliases: ADRB2 antibody, Alpha PAK antibody, Alpha-PAK antibody, MGC130000 antibody, MGC130001 antibody, p21 activated kinase 1 antibody, p21 protein (Cdc42/Rac) activated kinase 1 antibody, p21-activated kinase 1 antibody, p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related) antibody, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) antibody, p65 PAK antibody, p65-PAK antibody, P68-PAK antibody, PAK alpha antibody, PAK-1 antibody, Pak1 antibody, PAK1_HUMAN antibody, Paka antibody, PAKalpha antibody, Protein kinase MUK2 antibody, Rac/p21-activated kinase antibody, Serine/threonine-protein kinase PAK 1 antibody, STE20 homolog yeast antibody

UniProt

Q13153

途径

MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis