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PAK1 抗体 (Center)

Name: PAK1 抗体 (Center)
Brand: antibodies-online
SKU: ABIN2855705
Availability: OutOfStock

PAK1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

WB Image PAK1 antibody detects PAK1 protein by western blot analysis. (PAK1 抗体 (Center))

WB Image Sample (30 ug of whole cell lysate) A: A431 B: HeLa 7. (PAK1 抗体 (Center))

ICC/IF Image PAK1 antibody detects PAK1 protein at cytoplasm by immunofluorescent analysis. (PAK1 抗体 (Center))

IHC-P Image PAK1 antibody detects PAK1 protein on human hepatoma by immunohistochemical analysis. (PAK1 抗体 (Center))

IHC

6 images

(1 reference)

产品编号 ABIN2855705

发货至: 中国

Datasheet as PDF

抗原 See all PAK1 抗体

PAK1 (P21-Activated Kinase 1 (PAK1))
抗原表位
34

17

15

13

10

10

9

9

8

7

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Center
适用
173

94

82

7

5

4

4

3

3

2

1

1
人, 大鼠, 小鼠
宿主
166

4

1

1
兔
Compatible Secondaries
克隆类型
160

13
多克隆
标记
90

10

7

7

6

6

6

6

6

6

4

4

3

3

3

3

3
This PAK1 antibody is un-conjugated
应用范围
116

66

45

39

39

33

31

14

11

10

9

6

4

3

3

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

交叉反应

牛

交叉反应（详细）

Bovine (100 %)

产品特性

Rabbit Polyclonal antibody to PAK1 (p21 protein (Cdc42/Rac)-activated kinase 1)
PAK1 antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the center region of human PAK1. The exact sequence is proprietary.

亚型

IgG

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PAK1 适用: 人 WB, ELISA, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 4D1 unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 252-501) antibody
PAK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 1-240) antibody
PAK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (AA 401-430) antibody
PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Ser204) antibody
PAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (N-Term) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (pThr212) antibody
PAK1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) antibody
PAK1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-P21-Activated Kinase 1 (PAK1) (Thr423) antibody
PAK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*

说明

Positive Control: A431 , HeLa , BCL-1 , PC-12 , SH-SY5Y

限制

仅限研究用
状态

Liquid

浓度

0.48 mg/mL

缓冲液

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Cai, Zhang, Zhang, Chen, Hu: "Effect of Th9/IL-9 on the growth of gastric cancer in nude mice." in: OncoTargets and therapy, Vol. 12, pp. 2225-2234, (2019) (PubMed).
抗原

PAK1 (P21-Activated Kinase 1 (PAK1))

别名

PAK1 (PAK1 产品)

别名

X-PAK1 antibody, XPak1 antibody, pak antibody, pak-1 antibody, pakalpha antibody, PAKalpha antibody, AW045634 antibody, PAK-1 antibody, Paka antibody, p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog antibody, p21 (RAC1) activated kinase 1 antibody, p21 protein (Cdc42/Rac)-activated kinase 1 antibody, Serine/threonine-protein kinase pak-1 antibody, pak1.S antibody, PAK1 antibody, Pak1 antibody, pak-1 antibody

背景

PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Cytoplasm , Cell junction , focal adhesion

分子量

61 kDa

基因ID

5058

途径

MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis