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c-MET 抗体 (pTyr1003)

Name: c-MET 抗体 (pTyr1003)
SKU: ABIN2567068
Availability: OutOfStock

MET 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

产品编号 ABIN2567068

发货至: 中国

Datasheet as PDF

抗原 See all c-MET (MET) 抗体

c-MET (MET) (Met Proto-Oncogene (MET))
抗原表位
43

29

28

21

12

11

8

7

7

7

6

5

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr1003
适用
222

124

93

6

4

4

4

4

2

2

2

1

1

1

1
人, 小鼠, 大鼠
宿主
194

38

3

2
兔
Compatible Secondaries
克隆类型
190

47
多克隆
标记
126

19

11

11

6

6

6

6

6

6

6

6

2

2

2

2

2

2

2

2

2

2

2
This c-MET antibody is un-conjugated
应用范围
160

102

43

29

26

19

15

14

12

8

8

5

4

4

1

1

1
Western Blotting (WB)

特异性

The antibody detects endogenous level of c-Met only when phosphorylated at tyrosine 1003.

纯化方法

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

免疫原

c-Met (phospho Tyr1003) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1003 (V-D-Y (p)-R-A) derived from Human c-Met.

亚型

IgG

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MET 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5E9B7 unconjugated

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MET 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Met Proto-Oncogene (MET) (pTyr1349) antibody
MET 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1:500~1:1000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store antibody at -20°C for up to one year.
抗原

c-MET (MET) (Met Proto-Oncogene (MET))

别名

C-Met (MET 产品)

别名

AUTS9 antibody, HGFR antibody, RCCP2 antibody, c-Met antibody, AI838057 antibody, HGF antibody, Par4 antibody, Hgfr antibody, c-met antibody, MET antibody, C-MET antibody, met antibody, met-A antibody, MET proto-oncogene, receptor tyrosine kinase antibody, met proto-oncogene antibody, MET proto-oncogene, receptor tyrosine kinase L homeolog antibody, MET antibody, Met antibody, met.L antibody

背景

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.

分子量

155 kDa

基因ID

4233

NCBI登录号

NP_000236

UniProt

P08581

途径

RTK signaling, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor