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AKT3 抗体 (AA 119-136)

AKT3 适用: 人, 小鼠, 大鼠, 猴, 犬, 小鸡, Cow, Pig, Bat, 马, 兔, Gibbon, Gorilla WB, IHC 宿主: 小鼠 Monoclonal 66C1247-1 unconjugated
产品编号 ABIN2469638
发货至: 中国
  • 抗原 See all AKT3 抗体
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    抗原表位
    • 14
    • 9
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 119-136
    适用
    人, 小鼠, 大鼠, 猴, 犬, 小鸡, Cow, Pig, Bat, 马, 兔, Gibbon, Gorilla
    宿主
    • 84
    • 24
    • 1
    小鼠
    克隆类型
    • 75
    • 34
    单克隆
    标记
    • 55
    • 9
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKT3 antibody is un-conjugated
    应用范围
    • 88
    • 57
    • 38
    • 15
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Protein G Column
    免疫原
    AKT3 monoclonal antibody was raised against amino acids 119 - 136 of AKT3 (Human).
    克隆位点
    66C1247-1
    亚型
    IgG1
    Top Product
    Discover our top product AKT3 Primary Antibody
  • 应用备注
    AKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 0.05 % BSA, 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies avoid freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store AKT3 antibody at 4 °C or -20 °C.
  • 抗原
    AKT3 (V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
    别名
    AKT3 (AKT3 产品)
    别名
    MPPH antibody, PKB-GAMMA antibody, PKBG antibody, PRKBG antibody, RAC-PK-gamma antibody, RAC-gamma antibody, STK-2 antibody, AI851531 antibody, D930002M15Rik antibody, Nmf350 antibody, Pkbg antibody, AKT serine/threonine kinase 3 antibody, thymoma viral proto-oncogene 3 antibody, v-akt murine thymoma viral oncogene homolog 3b antibody, AKT3 antibody, Akt3 antibody, akt3b antibody
    背景
    Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.
    基因ID
    10000
    UniProt
    Q9Y243
    途径
    PI3K-Akt Signaling, RTK signaling, TLR signaling, Hepatitis C, VEGF Signaling
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