C-JUN 抗体 (pSer243)
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- 抗原 See all C-JUN (JUN) 抗体
- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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抗原表位
- pSer243
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C-JUN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- C-Jun (phospho-Ser243) antibody detects endogenous levels of c-Jun only when phosphorylated at serine 243.
- 纯化方法
- Immunoaffinity chromatography
- 免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243 (P-L-SP-P-I).
- Top Product
- Discover our top product JUN Primary Antibody
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anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated
anti-Jun Proto-Oncogene (JUN) (pThr91) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (pSer73) antibodyJUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (N-Term) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal 4A11 unconjugated
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- 应用备注
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Suitable for use in Western blot (1: 500approx. 1: 1000) and Immunohistochemistry (1: 50approx. 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody (in aliquots) at -20 °C.
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- 抗原
- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
- 别名
- AP-1 / C-Jun (JUN 产品)
- 背景
- The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39
- 基因ID
- 3725
- NCBI登录号
- NP_002219
- UniProt
- P05412
- 途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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