C-JUN 抗体 (pSer73)
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北京 101111
Quick Overview for C-JUN 抗体 (pSer73) (ABIN196612)
抗原
See all C-JUN (JUN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer73
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特异性
- This antibody detects endogenous levels of c-Jun only when phosphorylated at Serine 73.
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纯化方法
- Immunoaffinity Chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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免疫原
- The antiserum was produced against synthesized phosphopeptide derived from human c- Jun around the phosphorylation site of Serine 73 (L-A-Sp-P-E).
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anti-Jun Proto-Oncogene (JUN) (AA 31-331) antibody
JUN 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 5B1 unconjugated
anti-Jun Proto-Oncogene (JUN) (pThr91) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (AA 1-70) antibodyJUN 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Jun Proto-Oncogene (JUN) (pSer73) antibodyJUN 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) (N-Term) antibodyJUN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyJUN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 9F5 unconjugated
anti-Jun Proto-Oncogene (JUN) antibodyKD Validated JUN 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB5760 unconjugated
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应用备注
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Western blot: 1/500approx. 1/1000. Immunohistochemistry on Paraffin Sections: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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别名
- AP-1 / C-Jun
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背景
- The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39
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基因ID
- 3725
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NCBI登录号
- NP_002219
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UniProt
- P05412
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途径
- MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
抗原
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