Caspase 8 抗体 (C-Term)
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- 抗原 See all Caspase 8 (CASP8) 抗体
- Caspase 8 (CASP8)
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Caspase 8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 15 amino acid peptide from near the carboxy terminus human caspase-8 isoform E.
- Top Product
- Discover our top product CASP8 Primary Antibody
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anti-Caspase 8 (CASP8) (AA 411-482) antibody
CASP8 适用: 人, 小鼠, 大鼠, 猴, Pig, 绵羊 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) (AA 1-479) antibodyCASP8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) (AA 188-280) antibodyCASP8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) (AA 7-201) antibodyCASP8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) (AA 385-479) antibodyCASP8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) (AA 217-384) antibodyCASP8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) antibodyCASP8 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H11 unconjugated
anti-Caspase 8 (CASP8) (AA 410-449), (N-Term) antibodyCASP8 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 8 (CASP8) antibodyCASP8 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 小鼠 Monoclonal unconjugated
anti-Caspase 8 (CASP8) (AA 217-374) antibodyCASP8 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- Caspase 8 (CASP8)
- 别名
- Caspase-8 (CASP8 产品)
- 别名
- casp8-A antibody, xCaspase-8 antibody, casp8 antibody, CASP8 antibody, CASP-8 antibody, FLICE antibody, MACH antibody, Mch5 antibody, ALPS2B antibody, CAP4 antibody, Casp-8 antibody, MCH5 antibody, caspase-8 antibody, zgc:92075 antibody, caspase 8 L homeolog antibody, death related ced-3/Nedd2-like protein antibody, caspase 8 antibody, caspase-8 antibody, caspase-8-like antibody, caspase 8, apoptosis-related cysteine peptidase antibody, casp8.L antibody, LOC661095 antibody, CASP8 antibody, LOC5563818 antibody, casp8 antibody, LOC100222284 antibody, Casp8 antibody
- 背景
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Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies.Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens.The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death.Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex.The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation.FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis.This antibody will only detect isoform E of caspase-8.
Synonyms: FLICE, MACH, Mch5 - NCBI登录号
- NP_001219
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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