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C-JUN 抗体 (AA 41-70)

There are 3+ publications for this product available. The 兔 多克隆 anti-C-JUN antibody is suitable to detect C-JUN in samples from 人. It has been validated for WB.
产品编号 ABIN1881470
发货至: 中国
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Quick Overview for C-JUN 抗体 (AA 41-70) (ABIN1881470)

抗原

See all C-JUN (JUN) 抗体
C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

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宿主

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克隆类型

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多克隆

标记

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This C-JUN antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB11002
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    AA 41-70

    预测反应

    B, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from human JUN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Madhunapantula, Robertson: "Is B-Raf a good therapeutic target for melanoma and other malignancies?" in: Cancer research, Vol. 68, Issue 1, pp. 5-8, (2008) (PubMed).

    Fujita, Ito, Mizutani, Minoguchi, Yamamichi, Sakurai, Iba: "miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism." in: Journal of molecular biology, Vol. 378, Issue 3, pp. 492-504, (2008) (PubMed).

    Gan, Wang, Xi, Wu, Li, Li: "Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction." in: The Journal of cell biology, Vol. 180, Issue 6, pp. 1087-100, (2008) (PubMed).

  • 抗原

    C-JUN (JUN) (Jun Proto-Oncogene (JUN))

    别名

    JUN

    背景

    JUN interacts directly with specific target DNA sequences to regulate gene expression. Jun recognizes the AP-1 consensus sequence TGACTCA, a response element that confers sensitivity to one of the tumor-promoting Phorbol esters, 12-O-tetradecanoyl-phorbol-13-acetate (see also: TRE, TPA response element). Jun itself forms homodimers or heterodimers with junD and junB and also interacts with the oncogene product fos, forming jun-fos heterodimers.

    分子量

    35676

    NCBI登录号

    NP_002219

    UniProt

    P05412

    途径

    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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