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CHEK1 抗体 (AA 1-474)

This anti-CHEK1 antibody is a 绵羊多克隆 antibody detecting CHEK1 in WB. Suitable for 人, 小鼠, 大鼠和猴.

产品编号 ABIN187834

发货至: 中国

Quick Overview for CHEK1 抗体 (AA 1-474) (ABIN187834)

抗原

See all CHEK1 抗体

CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

177
113
61
16
11
7
7
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6
4
4
3
2
1
1

人, 小鼠, 大鼠, 猴

宿主

绵羊

克隆类型

多克隆

标记

122
11
9
8
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3

This CHEK1 antibody is un-conjugated

应用范围

164
82
55
41
40
33
32
21
16
10
7
6
4
3
3
1
1

Western Blotting (WB)

Discover our top product CHEK1 Primary Antibody

抗原表位
36

28

19

16

9

7

6

6

5

4

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-474

特异性

Recognizes chk1 kinase. Species Reactivity: Human, monkey, mouse, and rat, other species not tested. Molecular Weight: .54 kDa. Cellular Location: Cytoplasmic.

过滤

0.2 μm filtered

免疫原

GST fusion protein corresponding to amino acid sequence 1-474 of human chk1 kinase.
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer301) antibody
CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibody
CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer286) antibody
CHEK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibody
CHEK1 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 适用: 小鼠, 小鸡 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 1 (CHEK1) antibody
CHEK1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Monoclonal 2F2 unconjugated Recombinant Antibody

anti-Checkpoint Kinase 1 (CHEK1) antibody
CHEK1 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 2G1D5 unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 适用: 人 WB, IHC (p), DB 宿主: 兔 Polyclonal RB7845-RB18425 unconjugated

应用备注

Western blot: Use 1-10 µg/ml. The optimal dilution for a specific application should be determined by the researcher.

限制

仅限研究用
状态

Liquid

缓冲液

Provided as 0.2 µm sterile filtered solution in PBS with 0.08% sodium azide.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C
抗原

CHEK1 (Checkpoint Kinase 1 (CHEK1))

别名

CHK1

背景

One mechanism by which checkpoints maintain the fidelity of cell cycle events is through blocking mitosis in response to unreplicated or damaged DNA. In most species this occurs through inhibiting activation of the cyclic-dependent kinase cdc2, which regulates entry into mitosis. Chk1, a kinase involved in the DNA damage checkpoint response can phosphorylate Cdc25C an activator of cdc2. It is hypothesized that chk1 induces serine 216 phosphorylation of Cdc 25C and subsequent binding negatively regulated Cdc25C, thus preventing it from activating cdc2.

途径

p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair

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