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ATF2 抗体 (pThr51, pThr53, pThr69, pThr71)

ATF2 适用: 人, 小鼠, 大鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN155094
发货至: 中国
  • 抗原 See all ATF2 抗体
    ATF2 (Activating Transcription Factor 2 (ATF2))
    抗原表位
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    pThr51, pThr53, pThr69, pThr71
    适用
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    人, 小鼠, 大鼠
    宿主
    • 316
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    • 1
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    克隆类型
    • 309
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    多克隆
    标记
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    This ATF2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody detects phosphorylated ATF-2 (Thr69 and Thr71).
    纯化方法
    Purified
    Top Product
    Discover our top product ATF2 Primary Antibody
  • 应用备注
    Western Blot: 1-2 μg/mL. Immunoprecipitation: 10 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    ATF2 (Activating Transcription Factor 2 (ATF2))
    别名
    ATF2 (ATF2 产品)
    别名
    CRE-BP1 antibody, CREB2 antibody, HB16 antibody, TREB7 antibody, CG12850 antibody, CG3749 antibody, dATF-2 antibody, DmelCG30420 antibody, CG30420 antibody, CHN1 antibody, Atf-2 antibody, CRE-BP antibody, Creb2 antibody, D130078H02Rik antibody, D18875 antibody, Tg(Gzma-Klra1)7Wum antibody, mXBP antibody, atf2-A antibody, atf2l antibody, activating transcription factor 2 antibody, Activating transcription factor-2 antibody, activating transcription factor 2 S homeolog antibody, ATF2 antibody, Atf-2 antibody, Atf2 antibody, atf2.S antibody, atf2 antibody
    背景
    The transcription factor ATF-2 (also called CRE-BP1) is a member of the ATF/CREB family of leucine zipper proteins. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr69 and Thr71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr69 and Thr71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro.Synonyms: ATF-2, Activating transcription factor 2, CRE-BP1, CREB-2, CREB2, CREBP1, Cyclic AMP-dependent transcription factor ATF-2, Cyclic AMP-responsive element-binding protein 2, HB16, cAMP response element-binding protein CRE-BP1, cAMP-dependent transcription factor ATF-2
    基因ID
    1386
    NCBI登录号
    NP_001871
    UniProt
    P15336
    途径
    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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