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ATF2 抗体 (AA 93-450)

The 兔 多克隆 anti-ATF2 antibody (ABIN3043791) specifically detects ATF2 in WB, IHC, FACS 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN3043791
发货至: 中国
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Room 801-803
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Quick Overview for ATF2 抗体 (AA 93-450) (ABIN3043791)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ATF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 93-450

    原理

    Anti-ATF2 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human ATF2 shares 99% amino acid (aa) sequence identity with both mouse,rat ATF2.

    产品特性

    Anti-ATF2 Antibody. Tested in Flow Cytometry, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human ATF2 recombinant protein (Position: E93-E450). Human ATF2 shares 99% amino acid (aa) sequence identity with both mouse and rat ATF2.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    背景

    Background: ATF2, also known as Activating transcription factor 2, is a protein that in humans is encoded by the ATF2 gene. It is mapped to 2q31.1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus, it may represent a class of sequence-specific factors that activate transcription by effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.

    Gene Full Name: activating transcription factor 2

    Sequence Similarities: Belongs to the bZIP family. ATF subfamily.

    分子量

    65-70 kDa

    基因ID

    1386

    UniProt

    P15336

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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