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PTPN11 抗体 (pTyr542)

PTPN11 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN481806
发货至: 中国
  • 抗原 See all PTPN11 抗体
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    抗原表位
    • 32
    • 25
    • 15
    • 15
    • 9
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 508-557, pTyr542
    适用
    • 154
    • 116
    • 105
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 169
    • 14
    • 2
    • 1
    克隆类型
    • 149
    • 37
    多克隆
    标记
    • 88
    • 12
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PTPN11 antibody is un-conjugated
    应用范围
    • 121
    • 50
    • 42
    • 27
    • 26
    • 26
    • 20
    • 16
    • 14
    • 7
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性

    SHP-2 (Phospho-Tyr542) Antibody detects endogenous levels of SHP-2 only when phosphorylated at Tyr542.

    PhosphorylationH:Y542 M:Y546 R:Y542

    纯化方法
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    纯度
    > 95 %
    免疫原
    The antiserum was produced against synthesized peptide derived from human SHP-2 around the phosphorylation site of Tyr542.
    亚型
    IgG
    Top Product
    Discover our top product PTPN11 Primary Antibody
  • 应用备注
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
    说明

    Unigene-Number: Hs.506852, Hs.646231 (NCBI Gene Symbol: PTPN11)

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable at -20°C for at least 1 year.
    有效期
    12 months
  • 抗原
    PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
    别名
    SHP-2 (PTPN11 产品)
    别名
    BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
    物质类
    Viral Protein
    背景

    Synonyms: PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase, non-receptor type 11, SH-PTP2, SH-PTP3, SHPTP2

    NCBI Gene Symbol: PTPN11

    分子量
    68 kDa
    基因ID
    5781
    OMIM
    151100
    UniProt
    Q06124
    途径
    JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
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