PTPN11 抗体 (pTyr542)
-
- 抗原 See all PTPN11 抗体
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
-
抗原表位
- AA 508-557, pTyr542
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PTPN11 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
-
SHP-2 (Phospho-Tyr542) Antibody detects endogenous levels of SHP-2 only when phosphorylated at Tyr542.
PhosphorylationH:Y542 M:Y546 R:Y542
- 纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- 纯度
- > 95 %
- 免疫原
- The antiserum was produced against synthesized peptide derived from human SHP-2 around the phosphorylation site of Tyr542.
- 亚型
- IgG
- Top Product
- Discover our top product PTPN11 Primary Antibody
-
-
- 应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000
- 说明
-
Unigene-Number: Hs.506852, Hs.646231 (NCBI Gene Symbol: PTPN11)
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Stable at -20°C for at least 1 year.
- 有效期
- 12 months
-
- 抗原
- PTPN11 (Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
- 别名
- SHP-2 (PTPN11 产品)
- 别名
- BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
- 物质类
- Viral Protein
- 背景
-
Synonyms: PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase, non-receptor type 11, SH-PTP2, SH-PTP3, SHPTP2
NCBI Gene Symbol: PTPN11
- 分子量
- 68 kDa
- 基因ID
- 5781
- OMIM
- 151100
- UniProt
- Q06124
- 途径
- JAK/STAT Signaling, RTK signaling, TCR Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, Warburg Effect
-