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CHEK1 抗体 (pSer296) (Cy5.5)

This anti-CHEK1 antibody is a 兔 多克隆 antibody detecting CHEK1 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1407911
发货至: 中国

Quick Overview for CHEK1 抗体 (pSer296) (Cy5.5) (ABIN1407911)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CHEK1 antibody is conjugated to Cy5.5

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    pSer296

    交叉反应

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human CHEK1 isoform b around the phosphorylation site of Ser296

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    CHEK1

    背景

    Synonyms: Chk1 Ser296, Chk1 phospho S296,Chk1 Ser296, p-Chk1 phospho S296, Chk1S296, Cell cycle checkpoint kinase, Checkpoint, S. pombe, homolog of, 1, Checkpoint kinase 1, Checkpoint kinase 1 homolog S. pombe, CHEK 1, CHEK-1, CHEK1, Chk 1, Chk1, CHK1 checkpoint homolog S. pombe, EC 2.7.11.1, rad27, Serine/threonine protein kinase Chk1, Serine/threonine-protein kinase CHK1, STT3, subunit of the oligosaccharyltransferase complex, homolog A S. cerevisiae, C85740, CHK1_HUMAN.

    Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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