BAX 抗体 (AA 3-16)
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- 抗原 See all BAX 抗体
- BAX (BCL2-Associated X Protein (BAX))
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抗原表位
- AA 3-16
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BAX antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- 特异性
- Mouse Bax
- 产品特性
- Mouse Anti-Mouse Bax-UNLB
- 纯化方法
- Purified
- 免疫原
- Murine Bax peptide (a.a. 3-16)
- 克隆位点
- 5B7
- 亚型
- IgG1
- Top Product
- Discover our top product BAX Primary Antibody
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX 适用: 人, 小鼠, 大鼠, Pig, Cow, 兔, 小鸡, 斑马鱼 WB, ELISA, FACS, IP, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX 适用: 人, 小鼠, 大鼠, 猴, Pig, Cow, 兔, 犬, 小鸡, 绵羊, 马, 豚鼠, Hamster, 山羊, Avian, Cat, 驴 WB, IF 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyKO Validated BAX 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB0952 unconjugated
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- 应用备注
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Working Dilution:
Western Blotting: 1 µg/mL
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. - 样本量
- 1 mL
- 限制
- 仅限研究用
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- 缓冲液
- Product is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- 4 °C
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- 抗原
- BAX (BCL2-Associated X Protein (BAX))
- 别名
- Bax (BAX 产品)
- 别名
- BAX-ALPHA antibody, bax-A antibody, xBax antibody, xlbax antibody, BAX antibody, bax antibody, fj16e01 antibody, wu:fc50b10 antibody, wu:fj16e01 antibody, BCL2L4 antibody, zgc:112983 antibody, BCL2 associated X, apoptosis regulator antibody, BCL2-associated X protein L homeolog antibody, BCL2-associated X protein antibody, bcl2-associated X protein, a antibody, bcl2-associated X protein, b antibody, BAX antibody, bax.L antibody, bax antibody, baxa antibody, Bax antibody, baxb antibody
- 背景
- Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bax is a member of the Bcl-2 family of apoptosis-associated proteins and, although it is similar in structure to Bcl-2, Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial membranes, inducing mitochondrial damage and subsequent cell death in a caspase-independent manner, presumably via their ion channel-forming activity. These channels may then function to promote a mitochondrial permeability transition or to puncture the outer mitochondrial membrane. In addition to forming homodimer, Bax can heterodimerize with Bcl-2 and Bcl-XL proteins. This heterodimerization between pro- and anti-apoptotic family members may serve a titration function and act as a sensor for the programmed cell death program. Mab 5B7 is specific for mouse Bax.
- 途径
- p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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