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C-JUN 抗体 (pSer73)

The 兔 多克隆 anti-C-JUN antibody (ABIN127167) specifically detects C-JUN in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN127167
发货至: 中国
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Quick Overview for C-JUN 抗体 (pSer73) (ABIN127167)

抗原

See all C-JUN (JUN) 抗体
C-JUN (JUN) (Jun Proto-Oncogene (JUN))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This C-JUN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pSer73

    特异性

    The Phospho-c-Jun (Ser73) antibody detects only activated c-Jun when phosphorylated at Ser73. It does not react with non-phosphorylated c-Jun.

    纯化方法

    Affinity purified
  • 应用备注

    Western Blot: 1 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    C-JUN (JUN) (Jun Proto-Oncogene (JUN))

    别名

    AP-1 / C-Jun

    背景

    C-Jun is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals, such as growth factors and UV irradiation, stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c- Jun at Ser63/73.Synonyms: Activator protein 1, Proto-oncogene c-jun, Transcription factor AP1, V-jun avian sarcoma virus 17 oncogene homolog, p39

    基因ID

    3725

    NCBI登录号

    NP_002219

    UniProt

    P05412

    途径

    MAPK Pathway, RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins
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