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TBP 抗体 (Internal Region)

TBP 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1109204
发货至: 中国
  • 抗原 See all TBP 抗体
    TBP (TATA Box Binding Protein (TBP))
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-50, Internal Region
    适用
    • 67
    • 41
    • 39
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, Pig
    宿主
    • 49
    • 18
    • 2
    山羊
    克隆类型
    • 51
    • 18
    多克隆
    标记
    • 49
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TBP antibody is un-conjugated
    应用范围
    • 62
    • 27
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-TPQPIQNTNS LS
    特异性
    This antibody is expected to recognize both reported Isoforms (NP_003185.1, NP_001165556.1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine (Dog), Porcine, Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_003185.1, NP_001165556.1. Genename: TBP
    Top Product
    Discover our top product TBP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TBP (TATA Box Binding Protein (TBP))
    别名
    TBP (TATA-Box-Binding Protein) (TBP 产品)
    别名
    GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody
    背景
    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein TBP and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. TBP is also known to interact with with HIV-1 Tat protein.Synonyms: GTF2D1, TATA-binding factor, TATA-box factor, TF2D, TFIID, Transcription initiation factor TFIID TBP subunit
    分子量
    37.7 kDa (NP_003185.1).
    基因ID
    6908
    NCBI登录号
    NP_003185
    途径
    WNT signaling
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