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MANF 抗体

(Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors\; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related. [provided by RefSeq, Jun 2010].
MANF 抗体  (AA 25-182) MANF 抗体  (AA 25-182) MANF 抗体 (AA 25-182) (ABIN6143461)

MANF 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

MANF 抗体  (AA 28-182) MANF 抗体  (AA 28-182) MANF 抗体 (AA 28-182) (ABIN7426499)

MANF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated

MANF 抗体  (C-Term) MANF 抗体  (C-Term) MANF 抗体 (C-Term) (ABIN6990751)

KO Validated MANF 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

MANF 抗体 by Grade

Find MANF 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

MANF 抗体 by 适用

Find MANF 抗体 for a variety of species such as anti-Human MANF, anti-Mouse MANF, anti-Rat MANF. The species listed below are among those available. Click on a link to go to the corresponding products.

MANF 抗体 by 应用范围

Find MANF 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MANF 抗体 by 抗体来源

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MANF 抗体 by 抗原表位

Find MANF 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MANF 抗体 by 克隆形成能力

Find available monoclonal or polyclonal MANF 抗体. Click on a link to go to the corresponding products.

MANF 抗体 by 克隆

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MANF 抗体 by 标记

Find MANF 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MANF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN6143461
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7426499
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN6990751
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (3)
Cat. No. ABIN521690
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7159417
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
  • (1)
Cat. No. ABIN956417
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN2855274
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN521689
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN238606
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6746622
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN956418
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (2)
Cat. No. ABIN1859738
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (2)
Cat. No. ABIN2788136
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN7043330
Quantity 25 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN500226
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our MANF 抗体

Herranen, Ikäheimo, Lankinen, Pakarinen, Fritzsch, Saarma, Lindahl, Pirvola: "Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss." in: Cell death & disease, Vol. 11, Issue 2, pp. 100, (2020) (PubMed).

Lindahl, Chalazonitis, Palm, Pakarinen, Danilova, Pham, Setlik, Rao, Võikar, Huotari, Kopra, Andressoo, Piepponen, Airavaara, Panhelainen, Gershon, Saarma: "Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice." in: Neurobiology of disease, Vol. 134, pp. 104696, (2020) (PubMed).

Pakarinen, Danilova, Võikar, Chmielarz, Piepponen, Airavaara, Saarma, Lindahl: "MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System." in: eNeuro, Vol. 7, Issue 1, (2020) (PubMed).

Tseng, Danilova, Domanskyi, Saarma, Lindahl, Airavaara: "MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex." in: eNeuro, Vol. 4, Issue 5, (2018) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Chen, Sundvik, Rozov, Priyadarshini, Panula: "MANF regulates dopaminergic neuron development in larval zebrafish." in: Developmental biology, Vol. 370, Issue 2, pp. 237-49, (2012) (PubMed).

Lindholm, Voutilainen, Laurén, Peränen, Leppänen, Andressoo, Lindahl, Janhunen, Kalkkinen, Timmusk, Tuominen, Saarma: "Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo." in: Nature, Vol. 448, Issue 7149, pp. 73-7, (2007) (PubMed).

Petrova, Raibekas, Pevsner, Vigo, Anafi, Moore, Peaire, Shridhar, Smith, Kelly, Durocher, Commissiong: "MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons." in: Journal of molecular neuroscience : MN, Vol. 20, Issue 2, pp. 173-88, (2003) (PubMed).

Shridhar, Shridhar, Rivard, Siegfried, Pietraszkiewicz, Ensley, Pauley, Grignon, Sakr, Miller, Smith: "Mutations in the arginine-rich protein gene, in lung, breast, and prostate cancers, and in squamous cell carcinoma of the head and neck." in: Cancer research, Vol. 56, Issue 24, pp. 5576-8, (1997) (PubMed).

Shridhar, Rivard, Shridhar, Mullins, Bostick, Sakr, Grignon, Miller, Smith: "A gene from human chromosomal band 3p21.1 encodes a highly conserved arginine-rich protein and is mutated in renal cell carcinomas." in: Oncogene, Vol. 12, Issue 9, pp. 1931-9, (1996) (PubMed).

Aliases for MANF 抗体

mesencephalic astrocyte derived neurotrophic factor (MANF) 抗体
mesencephalic astrocyte-derived neurotrophic factor (Manf) 抗体
RNA binding motif protein 15B (RBM15B) 抗体
Mesencephalic astrocyte-derived neurotrophic factor (Manf) 抗体
mesencephalic astrocyte-derived neurotrophic factor (manf) 抗体
mesencephalic astrocyte derived neurotrophic factor (Manf) 抗体
mesencephalic astrocyte-derived neurotrophic factor S homeolog (manf.S) 抗体
3230402M22Rik 抗体
AA407711 抗体
AA408789 抗体
AA673178 抗体
anon-EST:ParkEST188 抗体
ARMET 抗体
Armet 抗体
armet 抗体
ARP 抗体
arp 抗体
ARP-like 抗体
CG7013 抗体
D18Mgi17 抗体
D17914 抗体
Dmel\\CG7013 抗体
DmMANF 抗体
im:6909481 抗体
MANF 抗体
manf 抗体
RBM15B 抗体
zgc:153327 抗体
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