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MANF 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects MANF in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2788136
发货至: 中国
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Quick Overview for MANF 抗体 (C-Term) (ABIN2788136)

抗原

See all MANF 抗体
MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 38
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兔

克隆类型

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多克隆

标记

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This MANF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    MANF Antibody - C-terminal region

    序列

    EKICEKLKKK DSQICELKYD KQIDLSTVDL KKLRVKELKK ILDDWGETCK

    预测反应

    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against MANF. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MANF
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59608-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

    别名

    MANF

    背景

    Background Information: MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of MANF gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

    Gene Name: Mesencephalic astrocyte-derived neurotrophic factor

    Alternative Symbols: ARP, ARMET

    Protein Name: cDNA FLJ77177, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA EMBL BAF84932.1

    分子量

    21kDa

    基因ID

    7873

    NCBI登录号

    NP_006001

    UniProt

    A8K878
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