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TNFSF15 蛋白

TNFSF15 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS-PAGE. Active
产品编号 ABIN7520577
发货至: 中国
  • 抗原 See all TNFSF15 蛋白
    TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 15
    • 8
    • 2
    • 2
    • 1
    资源
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Active Recombinant Human TNFSF15 Protein
    序列
    LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL
    特异性
    Leu72-Leu251
    纯度
    > 90 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 1.0 EU/μg of the protein by LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF15 Protein at 5 μg/mL (100 μL/well) can bind DCR3 with a linear range of 0.12-6.98 ng/mL.
    Top Product
    Discover our top product TNFSF15 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    浓度
    0.9 mg/mL
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 50 mM NaCl, 5 % glycerol, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原
    TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
    别名
    TNFSF15 (TNFSF15 产品)
    别名
    TTPAL Protein, TL1 Protein, TL1A Protein, VEGI Protein, VEGI192A Protein, Tl1 Protein, Tl1a Protein, Vegi Protein, tumor necrosis factor superfamily member 15 Protein, TNF superfamily member 15 Protein, tumor necrosis factor (ligand) superfamily, member 15 Protein, TNFSF15 Protein, Tnfsf15 Protein
    背景

    Description: The protein is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.

    Name: TNFSF15,TL1,TL1A,TNLG1B,VEGI,VEGI192A

    基因ID
    9966
    UniProt
    O95150
    途径
    Positive Regulation of Endopeptidase Activity, Autophagy
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