TNFSF15 Protein (AA 72-251) (His tag)
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- 抗原 See all TNFSF15 蛋白
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 72-251
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This TNFSF15 protein is labelled with His tag.
- 序列
- AA 72-251
- 产品特性
- Biotinylated Human TNFR2 / CD120b / TNFRSF1B Protein, His,Avitag™
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFSF15 蛋白
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- 应用备注
- MALS verified
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- 别名
- TL1A (TNFSF15 产品)
- 别名
- TTPAL Protein, TL1 Protein, TL1A Protein, VEGI Protein, VEGI192A Protein, Tl1 Protein, Tl1a Protein, Vegi Protein, tumor necrosis factor superfamily member 15 Protein, TNF superfamily member 15 Protein, tumor necrosis factor (ligand) superfamily, member 15 Protein, TNFSF15 Protein, Tnfsf15 Protein
- 背景
- TNF-like cytokine 1A (TL1A) and its receptors, death receptor 3 (DR3) and decoy receptor 3 (DcR3) are members of the TNF and TNF receptor superfamilies of proteins, respectively. Binding of APC-derived TL1A to lymphocytic DR3 provides co-stimulatory signals for activated lymphocytes. DR3 signaling affects not only the proliferative activity of and cytokine production by effector lymphocytes, but also critically influences the development and suppressive function of regulatory T-cells. Whereas, DcR3 restricts the function of the TL1A/DR3 complex: attenuating T-cell activation and downregulating the secretion of pro-inflammatory cytokines. Together with DR3 and DcR3, TL1A constitutes a cytokine system that actively interferes with the regulation of immune responses.
- 分子量
- 22.4 kDa
- 途径
- Positive Regulation of Endopeptidase Activity, Autophagy
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