NTRK3 Protein (Fc Tag,His tag)
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- 抗原 See all NTRK3 蛋白
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This NTRK3 protein is labelled with Fc Tag,His tag.
- 原理
- Active Recombinant Human Trk-C/NTRK3 Protein
- 序列
- CPANCVCSKT EINCRRPDDG NLFPLLEGQD SGNSNGNASI NITDISRNIT SIHIENWRSL HTLNAVDMEL YTGLQKLTIK NSGLRSIQPR AFAKNPHLRY INLSSNRLTT LSWQLFQTLS LRELQLEQNF FNCSCDIRWM QLWQEQGEAK LNSQNLYCIN ADGSQLPLFR MNISQCDLPE ISVSHVNLTV REGDNAVITC NGSGSPLPDV DWIVTGLQSI NTHQTNLNWT NVHAINLTLV NVTSEDNGFT LTCIAENVVG MSNASVALTV YYPPRVVSLE EPELRLEHCI EFVVRGNPPP TLHWLHNGQP LRESKIIHVE YYQEGEISEG CLLFNKPTHY NNGNYTLIAK NPLGTANQTI NGHFLKEPFP ESTDNFILFD EVSPTPPITV THKPEED
- 特异性
- Cys32-Asp428
- 纯度
- > 97 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 1.0 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human NTF3 at 2 μg/mL (100 μL/well) can bind Recombinant human TrkC with a linear range of 22-90 ng/mL.
- Top Product
- Discover our top product NTRK3 蛋白
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Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (AA 41-160) protein (GST tag)
NTRK3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) protein (His tag)NTRK3 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (Active) protein (His tag)NTRK3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- 抗原
- NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
- 别名
- Trk-C/NTRK3 (NTRK3 产品)
- 别名
- TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
- 背景
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Description: NT-3 growth factor receptor also known as neurotrophic tyrosine kinase receptor type 3 or TrkC tyrosine kinase or Trk-C receptor, is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in TrkC encoding gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Name: NTRK3,GP145-TrkC,TRKC,gp145(trkC)
- 基因ID
- 4916
- UniProt
- Q16288
- 途径
- RTK signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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