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NTRK3 Protein (Fc Tag)

NTRK3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092728
发货至: 中国
  • 抗原 See all NTRK3 蛋白
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    蛋白类型
    Recombinant
    宿主
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    资源
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    HEK-293 Cells
    标记
    This NTRK3 protein is labelled with Fc Tag.
    原理
    Recombinant human NTRK3 protein with C-terminal human Fc tag
    特异性
    NTRK3 (Cys32-Thr429) hFc (Glu99-Ala330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product NTRK3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    NTRK3 (Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3))
    别名
    NTRK3 (NTRK3 产品)
    别名
    TRKC Protein, gp145(trkC) Protein, trkC Protein, AW125844 Protein, Ntrk3_tv3 Protein, TrkC Protein, neurotrophic receptor tyrosine kinase 3 Protein, neurotrophic tyrosine kinase, receptor, type 3 Protein, NTRK3 Protein, Ntrk3 Protein
    背景
    Synonymes: gp145(trkC), GP145-TrkC, TRKC
    Description: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
    分子量
    predicted molecular mass of 70.9 kDa after removal of the signal peptide.The apparent molecular mass of NTRK3-hFc is 100-130 kDa due to glycosylation.
    UniProt
    Q16288
    途径
    RTK signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size
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