MICA Protein (AA 1-308) (His tag)
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- 抗原 See all MICA 蛋白
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-308
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MICA protein is labelled with His tag.
- 序列
- Met1-Gln308
- 产品特性
- A DNA sequence encoding theHuman MICA protein (Q96QC4) (Met1-Gln308) was expressed with a C-His.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product MICA 蛋白
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MHC Class I Polypeptide-Related Sequence A (MICA) protein (His-Avi Tag,Biotin)
MICA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-308) protein (His-Avi Tag)MICA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 1-284) protein (His tag)MICA 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MHC Class I Polypeptide-Related Sequence A (MICA) protein (His tag)MICA 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-308) (Active) protein (Fc Tag)MICA 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-306) protein (His tag)MICA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-307) protein (His tag)MICA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 1-383) protein (GST tag)MICA 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-307) protein (His tag)Crystallography grade MICA 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
MHC Class I Polypeptide-Related Sequence A (MICA) (AA 24-383) protein (rho-1D4 tag)Crystallography grade MICA 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- 别名
- MICA (MICA 产品)
- 别名
- MIC-A Protein, PERB11.1 Protein, MHC class I polypeptide-related sequence A Protein, MICA Protein
- 背景
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Background: MHC class I chain-related molecules A (MICA) is one of the genes in the HLA class I region, which belongs to the MHC class I family. It is the member of the non-classical class I family that displays the greatest degree of polymorphism. The MICA protein product is expressed on the cell surface, although unlike canonical class I molecules do not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. The Natural killer group 2D (NKG2D), a C-type lectin-like activating immunoreceptor, is a receptor of MICA, which was detected on most gamma-delta T cells, CD8+ alpha-beta T cells, and natural killer (NK) cells. Effector cells from all these subsets could be stimulated by the ligation of NKG2D. Engagement of NKG2D activated cytolytic responses of gamma-delta T cells and NK cells against transfectants and epithelial tumor cells expressing MICA. The MICA system is a novel, avidin-free immunohistochemical detection system that provides a significant increase in sensitivity compared to traditional immunodetection systems.
Synonym: MHC class I chain-related protein A,Stress inducible class I homolog,MHC class I polypeptide-related sequence A
- 分子量
- 33 kDa
- UniProt
- Q96QC4
- 途径
- Activation of Innate immune Response, Transition Metal Ion Homeostasis
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