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MICA Protein (His tag)

MICA 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
产品编号 ABIN6964102
发货至: 中国
  • 抗原 See all MICA 蛋白
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    蛋白类型
    Recombinant
    宿主
    • 22
    • 1
    资源
    • 11
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This MICA protein is labelled with His tag.
    应用范围
    ELISA
    原理
    Recombinant Human MICA Protein with C-terminal 6xHis tag
    特异性
    MICA (Glu24-Trp307) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product MICA 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    别名
    MICA (MICA 产品)
    别名
    MIC-A Protein, PERB11.1 Protein, MHC class I polypeptide-related sequence A Protein, MICA Protein
    背景
    Synonymes: MIC-A, PERB11.1
    Description: This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
    分子量
    predicted molecular mass of 33.5 kDa after removal of the signal peptide. The apparent molecular mass of MICA-His is 55-70 kDa due to glycosylation.
    基因ID
    100507436
    UniProt
    Q29983
    途径
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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