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MICA Protein (AA 24-308) (His-Avi Tag)

MICA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275255
发货至: 中国
  • 抗原 See all MICA 蛋白
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    蛋白类型
    Recombinant
    产品特性
    AA 24-308
    宿主
    • 22
    • 1
    资源
    • 11
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This MICA protein is labelled with His-Avi Tag.
    原理
    Human MICA Protein
    序列
    Glu24-Gln308
    产品特性
    Recombinant Human MICA Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu24-Gln308.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human MICA, His Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.20μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product MICA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    别名
    MICA (MICA 产品)
    别名
    MIC-A Protein, PERB11.1 Protein, MHC class I polypeptide-related sequence A Protein, MICA Protein
    背景
    MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85 % amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig-like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin..
    分子量
    35.8 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
    UniProt
    Q96QC4
    途径
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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