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CDK4 Protein (AA 2-303) (His tag)

CDK4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7504963
发货至: 中国
  • 抗原 See all CDK4 蛋白
    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
    蛋白类型
    Recombinant
    产品特性
    AA 2-303
    宿主
    • 11
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CDK4 protein is labelled with His tag.
    序列
    Ala2-Glu303
    产品特性
    A DNA sequence encoding the Human CDK4 (P11802-1) (Ala2-Glu303) was expressed with a polyhistidine tag at the N-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CDK4 蛋白
  • 说明

    used as Immunogen for (ABIN6999859)

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
    别名
    CDK4 (CDK4 产品)
    别名
    zgc:153726 Protein, CMM3 Protein, PSK-J3 Protein, Crk3 Protein, 8-6 Protein, CDK4 Protein, CDK4/6 Protein, CG5072 Protein, Cdk4/6 Protein, DmCdk4 Protein, Dmel\\CG5072 Protein, Pk53C Protein, Pk?7 Protein, cdk Protein, cdk4 Protein, cdk4/6 Protein, dCdk4 Protein, l(2)05428 Protein, l(2)0671 Protein, l(2)k06503 Protein, l(2)s4639 Protein, l(2)sh0671 Protein, xcdk4 Protein, cyclin-dependent kinase 4 Protein, cyclin dependent kinase 4 Protein, Cyclin-dependent kinase 4 Protein, cyclin-dependent kinase 4 L homeolog Protein, cdk4 Protein, CDK4 Protein, Cdk4 Protein, cdk4.L Protein
    背景

    Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

    Synonym: Cdk 4,cdk4,CDK4 protein,CDK4,Cell division kinase 4,Cell division protein kinase 4,CMM 3,CMM3,Crk3,Cyclin dependent kinase 4,Cyclin-dependent kinase 4,Melanoma cutaneous malignant 3,MGC14458,p34 cdk4,PSK J3,PSK-J3

    分子量
    33.5 kDa
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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