CDK4 蛋白
(Cyclin-Dependent Kinase 4 (CDK4))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
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20 results
CDK4
宿主: 人
宿主: 小麦胚
Recombinant
WB, ELISA, AA, AP
1 image
1 reference
CDK4
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 80 % as determined by reducing SDS-PAGE.
Latest Publications for our CDK4 蛋白
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).
Aliases for CDK4 蛋白
cyclin-dependent kinase 4 (cdk4) 蛋白cyclin dependent kinase 4 (CDK4) 蛋白
cyclin-dependent kinase 4 (Cdk4) 蛋白
cyclin dependent kinase 4 (Cdk4) 蛋白
Cyclin-dependent kinase 4 (Cdk4) 蛋白
cyclin-dependent kinase 4 L homeolog (cdk4.L) 蛋白
8-6 蛋白
cdk 蛋白
CDK4 蛋白
cdk4 蛋白
CDK4/6 蛋白
Cdk4/6 蛋白
cdk4/6 蛋白
CG5072 蛋白
CMM3 蛋白
Crk3 蛋白
dCdk4 蛋白
DmCdk4 蛋白
Dmel\\CG5072 蛋白
l(2)05428 蛋白
l(2)0671 蛋白
l(2)k06503 蛋白
l(2)s4639 蛋白
l(2)sh0671 蛋白
Pk53C 蛋白
Pk?7 蛋白
PSK-J3 蛋白
xcdk4 蛋白
zgc:153726 蛋白
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