CDK2 蛋白
(Cyclin-Dependent Kinase 2 (CDK2))
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| CDK2 Protein (AA 1-346) (His tag) | 小鼠 | HEK-293 Cells |
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| CDK2 Protein (AA 1-298) (His tag) | 人 | HEK-293 Cells |
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| CDK2 Protein (AA 1-298) (GST tag) | 人 | 小麦胚 |
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| CDK2 Protein (AA 1-298) (His tag) | 人 | Baculovirus infected Insect Cells |
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| CDK2 Protein (AA 1-346) (Strep Tag) | 小鼠 | Cell-free protein synthesis (CFPS) |
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| CDK2 Protein (DYKDDDDK Tag) | 人 | Baculovirus infected Insect Cells |
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| CDK2 Protein (GST tag) | 人 | Baculovirus infected Insect Cells |
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| CDK2 Protein (AA 1-298) (Strep Tag) | 人 | Cell-free protein synthesis (CFPS) |
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| CDK2 Protein (AA 1-198) (His-IF2DI Tag) | 人 | 大肠杆菌（E. Coli） |
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| CDK2 蛋白 | 人 | 大肠杆菌（E. Coli） |
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| CDK2 蛋白 | 人 | Insect Cells |
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| CDK2 Protein (His tag) | 人 | Baculovirus infected Insect Cells |
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| CDK2 Protein (AA 1-298) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 94-212) (His tag,GST tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 93-211) (His tag,GST tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 94-198) (His tag,GST tag) | 人 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 93-211) (MBP tag,His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 94-212) (His tag) | 大鼠 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 5-294) (His tag) | 人 | 大肠杆菌（E. Coli） |
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| CDK2 Protein (AA 5-346) (His tag) | 小鼠 | 大肠杆菌（E. Coli） |
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Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- PS (Protein Structure: 有验证图片)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- HEK-293 Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Protein
- SDS (SDS-PAGE: 有验证图片)
- AP (Affinity Purification: 所列应用)
- AA (Antibody Array: 所列应用)
- ELISA (ELISA: 所列应用)
- WB (Western Blotting: 所列应用)
2 references - 宿主
- 人
- 宿主
- 小麦胚
- 蛋白类型
- Recombinant
Protein
- SDS (SDS-PAGE: 有验证图片)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 小鼠
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- NC (Negative Control: 所列应用)
- S (Substrate: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Inactive
Protein
- NC (Negative Control: 所列应用)
- S (Substrate: 所列应用)
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 生物活性
- Inactive
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 质量等级
- custom-made
- 宿主
- 人
- 宿主
- Cell-free protein synthesis (CFPS)
- 蛋白类型
- Recombinant
- 纯度
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- Greater than 90 % as determined by SDS-PAGE.
Protein
- 宿主
- 人
- 宿主
- Baculovirus infected Insect Cells
- 蛋白类型
- Recombinant
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 90 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 大鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 97 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 人
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Protein
- SDS (SDS-PAGE: 所列应用)
- WB (Western Blotting: 所列应用)
- Imm (Immunogen: 所列应用)
- PC (Positive Control: 所列应用)
- 宿主
- 小鼠
- 宿主
- 大肠杆菌（E. Coli）
- 蛋白类型
- Recombinant
- 纯度
- > 95 %
Latest Publications for our CDK2 蛋白
: "TarIKGC: A Target Identification Tool Using Semantics-Enhanced Knowledge Graph Completion with Application to CDK2 Inhibitor Discovery." in: Journal of medicinal chemistry, Vol. 68, Issue 2, pp. 1793-1809, (2025) (PubMed).
: "A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization." in: Human mutation, Vol. 31, Issue 11, pp. E1825-35, (2010) (PubMed).
: "Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms." in: Analytical chemistry, Vol. 81, Issue 9, pp. 3314-20, (2009) (PubMed).
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).
: "A novel germline CDKN1B mutation causing multiple endocrine tumors: clinical, genetic and functional characterization." in: Human mutation, Vol. 31, Issue 11, pp. E1825-35, (2010) (PubMed).
: "Peptide aptamers in label-free protein detection: 2. Chemical optimization and detection of distinct protein isoforms." in: Analytical chemistry, Vol. 81, Issue 9, pp. 3314-20, (2009) (PubMed).
: "Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"." in: Molecular and cellular biology, Vol. 26, Issue 13, pp. 5070-85, (2006) (PubMed).
Aliases for CDK2 蛋白
cyclin dependent kinase 2 (CDK2) 蛋白cyclin-dependent kinase 2 (Cdk2) 蛋白
cyclin dependent kinase 2 (Cdk2) 蛋白
cyclin-dependent kinase 2 (cdk2) 蛋白
cyclin-dependent kinase 2 S homeolog (cdk2.S) 蛋白
cyclin-dependent kinase 2 (CDK2) 蛋白
A630093N05Rik 蛋白
cdk2L 蛋白
CDKN2 蛋白
eg1 蛋白
p33(CDK2) 蛋白
wu:fa10c02 蛋白
zgc:56598 蛋白
zgc:77684 蛋白
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