CDK2 Protein (AA 1-298) (His tag)
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- 抗原 See all CDK2 蛋白
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-298
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CDK2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MENFQKVEKI GEGTYGVVYK ARNKLTGEVV ALKKIRLDTE TEGVPSTAIR EISLLKELNH PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP LPLIKSYLFQ LLQGLAFCHS HRVLHRDLKP QNLLINTEGA IKLADFGLAR AFGVPVRTYT HEVVTLWYRA PEILLGCKYY STAVDIWSLG CIFAEMVTRR ALFPGDSEID QLFRIFRTLG TPDEVVWPGV TSMPDYKPSF PKWARQDFSK VVPPLDEDGR SLLSQMLHYD PNKRISAKAA LAHPFFQDVT KPVPHLRLLE HHHHHH
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product CDK2 蛋白
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Cyclin-Dependent Kinase 2 (CDK2) (AA 1-298) protein (GST tag)
CDK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 2 (CDK2) (AA 1-198) protein (His tag)CDK2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cyclin-Dependent Kinase 2 (CDK2) (AA 211-298) protein (GST tag)CDK2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In Phosphate buffered saline ( pH 7.4), 30 % glycerol, 2 mM DTT, 0.1 mM PMSF
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- 别名
- CDK2 (CDK2 产品)
- 别名
- p33(CDK2) Protein, A630093N05Rik Protein, wu:fa10c02 Protein, zgc:56598 Protein, zgc:77684 Protein, eg1 Protein, CDKN2 Protein, cdk2L Protein, cyclin dependent kinase 2 Protein, cyclin-dependent kinase 2 Protein, cyclin-dependent kinase 2 S homeolog Protein, CDK2 Protein, Cdk2 Protein, cdk2 Protein, cdk2.S Protein
- 背景
- Cyclin-dependent kinase 2, also known as CDK2, phosphorylates CTNNB1, uSP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. This protein acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression, controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. This protein is crucial role in orchestrating a fine balance between cellular proliferation, cell death, and DNA repair in human embryonic stem cells (hESCs). Recombinant human CDK2 protein, fused to His-tag at C-terminus, was expressed in insect cells using baculovirus expression system and purified by using conventional chromatography techniques.
- 分子量
- 34.9 kDa (306aa)
- NCBI登录号
- NP_001789
- UniProt
- P24941
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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