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CDK2 产品

(Cyclin-Dependent Kinase 2 (CDK2))

Categories

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq, Jul 2008].

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Featured CDK2 Categories

CDK2 抗体

High quality antibodies with extensive validation data.

CDK2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CDK2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (1)
  • (7)
Cat. No. ABIN969506
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (6)
Cat. No. ABIN560288
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, FACS, IF
Validations
  • (6)
Cat. No. ABIN1497399
Quantity 100 μL
Datasheet Datasheet

Recommended CDK2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (6)
Cat. No. ABIN6730873
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966164
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966163
Quantity 96 tests
Datasheet Datasheet

Recommended CDK2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
Cat. No. ABIN1348934
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569590
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122527
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CDK2 Products

Liang, Sun, Zhao, Zhang, Gu, Dong, Zhang, Sun, Sun: "Rictor regulates the vasculogenic mimicry of melanoma via the AKT-MMP-2/9 pathway." in: Journal of cellular and molecular medicine, Vol. 21, Issue 12, pp. 3579-3591, (2018) (PubMed).

Huang, Song, Tao, Shao, Zeng, Xu, Qi, Sun: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." in: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).

Zheng, Yu, Chen, Lu, Fan: "Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice." in: Scientific reports, Vol. 8, Issue 1, pp. 2832, (2018) (PubMed).

Liu, Lin, Mi, Li, Zhang: "Grape Seed Proanthocyanidin Extract Prevents Ovarian Aging by Inhibiting Oxidative Stress in the Hens." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 9390810, (2018) (PubMed).

Chen, Xu, Yang, Zhang, Wu, Chen, Li, Wang, Li, Li, Dai: "Upregulation of miR-223 in the rat liver inhibits proliferation of hepatocytes under simulated microgravity." in: Experimental & molecular medicine, Vol. 49, Issue 6, pp. e348, (2018) (PubMed).

Li, Kang, Yin, Li, Chen, Li, Zhang, Qiu: "Ginsenoside Rh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 3062-3068, (2018) (PubMed).

Mlcochova, Sutherland, Watters, Bertoli, de Bruin, Rehwinkel, Neil, Lenzi, Kim, Khwaja, Gage, Georgiou, Chittka, Yona, Noursadeghi, Towers, Gupta: "A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages." in: The EMBO journal, Vol. 36, Issue 5, pp. 604-616, (2017) (PubMed).

Hassan, Georgey, George, Mohammed: "Construction of some cytotoxic agents with aurone and furoaurone scaffolds." in: Future medicinal chemistry, Vol. 10, Issue 1, pp. 27-52, (2017) (PubMed).

Ren, Qiu, Lü, Ru, Li, Xiang, Yu, Zhang: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).

Han, Ge, Zhang, Zhou, Ji, Yang, Zhang: "Effects of tripterygium glycosides on restenosis following endovascular treatment." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4959-68, (2017) (PubMed).

Synonyms and alternative names related to CDK2

cyclin dependent kinase 2 (CDK2), cyclin-dependent kinase 2 (Cdk2), cyclin dependent kinase 2 (Cdk2), cyclin-dependent kinase 2 (cdk2), cyclin-dependent kinase 2 S homeolog (cdk2.S), cyclin-dependent kinase 2 (CDK2), A630093N05Rik, cdk2L, CDKN2, eg1, p33(CDK2), wu:fa10c02, zgc:56598, zgc:77684

Protein level used designations for CDK2

  • cdc2-related protein kinase
  • cell devision kinase 2
  • cell division protein kinase 2
  • p33 protein kinase
  • cyclin dependent kinase 2-alpha
  • cyclin-dependent kinase 2
  • CDC2 homolog Eg1 protein kinase
  • Cell division protein kinase 2
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