CDKN1C 蛋白
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
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CDKN1C
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for CDKN1C 蛋白
cyclin dependent kinase inhibitor 1C (CDKN1C) 蛋白cyclin-dependent kinase inhibitor 1Ca (cdkn1ca) 蛋白
cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c) 蛋白
cyclin-dependent kinase inhibitor 1C (Cdkn1c) 蛋白
AL024410 蛋白
BWCR 蛋白
BWS 蛋白
cb961 蛋白
CDKI 蛋白
KIP2 蛋白
Kip2 蛋白
p27Xic1-a 蛋白
p57 蛋白
p57(kip2) 蛋白
p57Kip2 蛋白
p57KIP2 蛋白
WBS 蛋白
zgc:86618 蛋白
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