CDK4 Protein (Myc-DYKDDDDK Tag)
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- 抗原 See all CDK4 蛋白
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CDK4 protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human CDK4 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CDK4 蛋白
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Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) protein (GST tag)
CDK4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) (Active) protein (GST tag)CDK4 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Cyclin-Dependent Kinase 4 (CDK4) (AA 4-303) (Active) protein (His tag)CDK4 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Cyclin-Dependent Kinase 4 (CDK4) (AA 4-303) (Active) protein (GST tag)CDK4 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Cyclin-Dependent Kinase 4 (CDK4) (AA 207-303) protein (His-IF2DI Tag)CDK4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) protein (His tag)CDK4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cyclin-Dependent Kinase 4 (CDK4) (AA 211-303) protein (GST tag)CDK4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase 4 (CDK4) (AA 2-303) protein (His tag)Crystallography grade CDK4 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
- 别名
- Cdk4 (CDK4 产品)
- 别名
- zgc:153726 Protein, CMM3 Protein, PSK-J3 Protein, Crk3 Protein, 8-6 Protein, CDK4 Protein, CDK4/6 Protein, CG5072 Protein, Cdk4/6 Protein, DmCdk4 Protein, Dmel\\CG5072 Protein, Pk53C Protein, Pk?7 Protein, cdk Protein, cdk4 Protein, cdk4/6 Protein, dCdk4 Protein, l(2)05428 Protein, l(2)0671 Protein, l(2)k06503 Protein, l(2)s4639 Protein, l(2)sh0671 Protein, xcdk4 Protein, cyclin-dependent kinase 4 Protein, cyclin dependent kinase 4 Protein, Cyclin-dependent kinase 4 Protein, cyclin-dependent kinase 4 L homeolog Protein, cdk4 Protein, CDK4 Protein, Cdk4 Protein, cdk4.L Protein
- 背景
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
- 分子量
- 33.5 kDa
- NCBI登录号
- NP_000066
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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