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NAMPT Protein (AA 1-491) (His tag)

NAMPT 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7504927
发货至: 中国
  • 抗原 See all NAMPT 蛋白
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    蛋白类型
    Recombinant
    产品特性
    AA 1-491
    宿主
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    资源
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This NAMPT protein is labelled with His tag.
    序列
    Met1-His491
    产品特性
    Recombinant Human PBEF is produced by our E.coli expression system and the target gene encoding Met1-His491 is expressed with a 6His tag at the N-terminus.
    纯度
    >90 % as determined by reducing SDS-PAGE.
    内毒素水平
    <1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product NAMPT 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    别名
    PBEF (NAMPT 产品)
    别名
    1110035O14Rik Protein, PBEF Protein, PBEF1 Protein, VF Protein, VISFATIN Protein, AI314458 Protein, AI480535 Protein, NAmPRTase Protein, Pbef Protein, Pbef1 Protein, Visfatin Protein, visfatin Protein, pbef Protein, pbef1 Protein, nicotinamide phosphoribosyltransferase Protein, Nicotinamide phosphoribosyltransferase Protein, nicotinamide phosphoribosyltransferase S homeolog Protein, NAMPT Protein, Nampt Protein, nampt Protein, Smon_0680 Protein, Mrub_2845 Protein, Cseg_3704 Protein, BC1002_3997 Protein, Ftrac_2686 Protein, Varpa_5681 Protein, Celal_3900 Protein, Deima_0880 Protein, BC1001_3724 Protein, Celly_1696 Protein, Clole_1542 Protein, Tsp_05934 Protein, nampt.S Protein
    背景

    Background: Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine ""visfatin"". PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has been shown to increase inflammatory cytokines, such as TNF-α, IL-1β, IL-16, and TGF-β1. PBEF also increases the production of IL-6, TNF-α, and IL-1β in CD14+ monocyctes, macrophages, and dendritic cells, enhances the effectiveness of T cells.

    Synonym: Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1, Visfatin, NAMPT, PBEF, PBEF1

    分子量
    57 kDa
    UniProt
    P43490
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