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NAMPT Protein (AA 1-491) (DYKDDDDK Tag)

NAMPT 宿主: 大鼠 宿主: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS
产品编号 ABIN1344283
发货至: 中国
  • 抗原 See all NAMPT 蛋白
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    蛋白类型
    Recombinant
    产品特性
    AA 1-491
    宿主
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    大鼠
    资源
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This NAMPT protein is labelled with DYKDDDDK Tag.
    应用范围
    SDS-PAGE (SDS)
    交叉反应
    大鼠
    产品特性
    Rat Nampt (visfatin/PBEF) (aa 1-491) is fused at the N-terminus to a FLAG®-tag.
    纯度
    >90 % (SDS-PAGE)
    过滤
    0.2 μm filtered
    内毒素水平
    <0.1EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product NAMPT 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    0.2μm-filtered solution in PBS, pH 7.2.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Working aliquots are stable for up to 3 months when stored at -20°C.
    有效期
    3 months
  • Spinnler, Gorski, Stolz, Schuster, Garten, Beck-Sickinger, Engelse, de Koning, Körner, Kiess, Maedler: "The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion." in: PLoS ONE, Vol. 8, Issue 1, pp. e54106, (2013) (PubMed).

  • 抗原
    NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))
    别名
    Nampt (Visfatin/PBEF) (NAMPT 产品)
    别名
    1110035O14Rik Protein, PBEF Protein, PBEF1 Protein, VF Protein, VISFATIN Protein, AI314458 Protein, AI480535 Protein, NAmPRTase Protein, Pbef Protein, Pbef1 Protein, Visfatin Protein, visfatin Protein, pbef Protein, pbef1 Protein, nicotinamide phosphoribosyltransferase Protein, Nicotinamide phosphoribosyltransferase Protein, nicotinamide phosphoribosyltransferase S homeolog Protein, NAMPT Protein, Nampt Protein, nampt Protein, Smon_0680 Protein, Mrub_2845 Protein, Cseg_3704 Protein, BC1002_3997 Protein, Ftrac_2686 Protein, Varpa_5681 Protein, Celal_3900 Protein, Deima_0880 Protein, BC1001_3724 Protein, Celly_1696 Protein, Clole_1542 Protein, Tsp_05934 Protein, nampt.S Protein
    背景
    Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52 kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
    分子量
    ~60kDa (SDS-PAGE)
    UniProt
    Q80Z29
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