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GTPase NRas Protein (NRAS) (AA 1-186) (His tag)

NRAS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
产品编号 ABIN7504485
发货至: 中国
  • 抗原 See all GTPase NRas (NRAS) 蛋白
    GTPase NRas (NRAS)
    蛋白类型
    Recombinant
    产品特性
    AA 1-186
    宿主
    • 4
    • 1
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    • 1
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    资源
    • 7
    • 2
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    • 1
    大肠杆菌(E. Coli)
    标记
    This GTPase NRas protein is labelled with His tag.
    原理
    Human NRAS Protein
    序列
    Met1-Cys186
    产品特性
    Recombinant Human NRAS Protein is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Cys186.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product NRAS 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GTPase NRas (NRAS)
    别名
    NRAS (NRAS 产品)
    别名
    NRAS Protein, AV095280 Protein, N-ras Protein, ALPS4 Protein, NRAS1 Protein, NS6 Protein, N-RAS Protein, fj99a10 Protein, wu:fj99a10 Protein, zgc:100761 Protein, zras-b1 Protein, H-RAS Protein, HRAS Protein, GTPase NRas Protein, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog Protein, NRAS proto-oncogene, GTPase Protein, neuroblastoma ras oncogene Protein, neuroblastoma RAS viral oncogene homolog Protein, Tsp_01117 Protein, nras.L Protein, Nras Protein, NRAS Protein, nras Protein
    背景
    NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.
    分子量
    22.29 kDa same as Tris-Bis PAGE result.
    UniProt
    P01111
    途径
    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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