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CRLF2 Protein (Fc Tag)

CRLF2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
产品编号 ABIN7275803
发货至: 中国
  • 抗原 See all CRLF2 蛋白
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 8
    • 1
    • 1
    资源
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CRLF2 protein is labelled with Fc Tag.
    序列
    Gly25-Lys231
    纯度
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human TSLP (R127A, R130A) at 1μg/ml (100μl/Well). Dose response curve for Human TSLPR, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    TSLPR (CRLF2 产品)
    别名
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    背景
    TSLP receptor, TSLPR, CRL2, CRLF2Y, CRLF2, IL-XR, p2RY8/CRLF2 fusion, CRLF2,Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
    分子量
    50.8 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Tris-Bis PAGE result.
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