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CRLF2 Protein (His tag)

CRLF2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320658
发货至: 中国
  • 抗原 See all CRLF2 蛋白
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    蛋白类型
    Recombinant
    宿主
    • 12
    • 7
    • 1
    • 1
    小鼠
    资源
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    人细胞
    标记
    This CRLF2 protein is labelled with His tag.
    原理
    Recombinant Mouse TSLP Receptor/CRLF2 Protein (His Tag)
    序列
    Ala20-Leu233
    产品特性
    Recombinant Mouse Thymic stromal lymphopoietin protein receptor is produced by our Mammalian expression system and the target gene encoding Ala20-Leu233 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CRLF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    TSLP Receptor/CRLF2 (CRLF2 产品)
    别名
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    背景

    Background: The cytokine thymic stromal lymphopoietin receptor (TSLPR) is consisting of a common γ receptor-like chain (TSLPR-γ) and a common interleukin 7 (IL-7) Rα chain that belongs to the type 1 cytokine receptor family. Transfection of TSLPR cDNA result in only low affinity binding, while cotransfection of the IL-7Rα chain cDNA shows high affinity binding. TSLP and TSLPR play a critical role in the initiation of allergic diseases in mice. The TSLP R cDNA encodes a transmembrane receptor containing 370 amino acids (aa) with two potential N-linked glycosylation sites and a cytoplasmic domain of 104 aa including a single tyrosine residue. TSLPR can mediate signaling of the signal transducer and activator of transcription 5 (Stat5) by TSLP. TSLP R is broadly expressed in the immune and hematopoietic cells, particularly in hematopoietic progenitors and myeloid cells.

    Synonym: CRL2, CRLF2, CRL2 cytokine receptor, Cytokine receptor-like 2, cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, Thymic stromal lymphopoietin protein receptor, Thymic stromal-derived lymphopoietin receptor, TSLP receptor, TSLPR

    分子量
    23.7 kDa
    UniProt
    Q8CII9
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