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CRLF2 Protein (AA 25-231) (His tag)

CRLF2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7275802
发货至: 中国
  • 抗原 See all CRLF2 蛋白
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    蛋白类型
    Recombinant
    产品特性
    AA 25-231
    宿主
    • 11
    • 8
    • 1
    • 1
    资源
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CRLF2 protein is labelled with His tag.
    原理
    Human TSLPR Protein
    序列
    Gly25-Lys231
    产品特性
    Recombinant Human TSLPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Lys231.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human TSLPR, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CRLF2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    别名
    TSLPR (CRLF2 产品)
    别名
    CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
    背景
    TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR) and IL-7 receptor-α, which polarize dendritic cells to induce type 2 inflammation and directly expand and/or activate Th2 cells, group 2 innate lymphoid cells, basophils, and other immune cells.
    分子量
    25.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
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