CRLF2 Protein (Fc Tag)
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- 抗原 See all CRLF2 蛋白
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This CRLF2 protein is labelled with Fc Tag.
- 原理
- Recombinant Human TSLP R/CRLF2 (C-Fc)
- 序列
- Gly25-Lys231
- 产品特性
- Recombinant Human CRLF2 is produced by our Mammalian expression system and the target gene encoding Gly25-Lys231 is expressed with a Fc tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Loaded Human TSLP-His(Cat#C00K) on HIS1K Biosensor, can bind Human TSLP R-Fc(Cat#CW56) with an affinity constant of 37.97nM as determined in BLI assay.
- Top Product
- Discover our top product CRLF2 蛋白
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Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)
CRLF2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) protein (His tag)CRLF2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)CRLF2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 25-231) (Active) protein (Fc Tag)CRLF2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) protein (GST tag)CRLF2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cytokine Receptor-Like Factor 2 (CRLF2) protein (His tag)CRLF2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) protein (Fc Tag)CRLF2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) protein (His tag)Crystallography grade CRLF2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 253-371) protein (His tag)Crystallography grade CRLF2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cytokine Receptor-Like Factor 2 (CRLF2) (AA 20-232) protein (His tag)Crystallography grade CRLF2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 别名
- TSLP R/CRLF2 (CRLF2 产品)
- 别名
- CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
- 背景
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Background: Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system. TSLP R expression is ubiquitous in the immune and hematopoietic cells, but is up-regulated in Th2-skewed cells. Cells expressing TSLP R alone bind TSLP with low affinity. Co-expression of TSLP R and IL-7 R alpha is required for high-affinity TSLP binding and signal transduction . The TSLP R and IL-7 R alpha are coexpressed primarily on monocytes and dendritic cells and at lower levels in lymphoid cells. TSLP has been shown to induce the release of T cell-attracting chemokines from monocytes and enhance the maturation of CD11c+ dendritic cells.
Synonym: CRL2, CRL2cytokine receptor CRL2 precusor, CRLF2, CRLF2Y, CRLM-2, Cytokine receptor-like 2,cytokine receptor-like factor 2, ILXR, IL-XR, P2RY8/CRLF2 fusion, PCOR1, TSLP R, TSLP receptor,TSLPR
- 分子量
- 50.9 kDa
- UniProt
- Q9HC73
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