This SIGLEC15 protein is labelled with His tag,Biotin.
原理
Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling)
序列
Arg24-Thr262
产品特性
Recombinant Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg24-Thr262.
SIGLEC15
宿主: Cynomolgus
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as 0.22μm filtered solution in 20 mM PB, 0.5M NaCl, 0.1M L-arginine ( pH 7.4).
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
分子量
26.7 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result.