SIGLEC15 Protein (AA 60-322) (His-Avi Tag)
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- 抗原 See all SIGLEC15 蛋白
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- 蛋白类型
- Recombinant
- 产品特性
- AA 60-322
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This SIGLEC15 protein is labelled with His-Avi Tag.
- 原理
- Cynomolgus Siglec-15/CD33L3 Protein
- 序列
- Met60-Thr322
- 产品特性
- Recombinant Cynomolgus Siglec-15/CD33L3 Protein is expressed from HEK293 with His and Avi tag at the C-Terminus.It contains Met60-Thr322.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus Siglec-15, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Siglec-15 Antibody, hFc Tag with the EC50 of 16.7ng/ml determined by ELISA. See testing image for detail.
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Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) protein (His-Avi Tag)
SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 60-322) protein (His-Avi Tag,Biotin)SIGLEC15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 24-260) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (mFc Tag)SIGLEC15 宿主: 人 宿主: 人细胞 Recombinant >90 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 宿主: Cynomolgus 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (Fc Tag)SIGLEC15 宿主: Cynomolgus 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) (Active) protein (Fc Tag)SIGLEC15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) (Active) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl, 0.1M L-arginine ( pH 6.0).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- 别名
- Siglec-15 (SIGLEC15 产品)
- 别名
- RGD1565948 Protein, CD33L3 Protein, HsT1361 Protein, SIGLEC-15 Protein, Cd33l3 Protein, EG620235 Protein, SIGLEC-I Protein, sialic acid binding Ig-like lectin 15 Protein, sialic acid binding Ig like lectin 15 Protein, Siglec15 Protein, SIGLEC15 Protein
- 背景
- Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
- 分子量
- 29.2 kDa. Due to glycosylation, the protein migratesto 33-43 kDa based on Tris-Bis PAGE result.
- NCBI登录号
- XP_005586866
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