SIGLEC15 Protein (Fc Tag)
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- 抗原 See all SIGLEC15 蛋白
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- Cynomolgus
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资源
- 人细胞
- 标记
- This SIGLEC15 protein is labelled with Fc Tag.
- 原理
- Recombinant Cynomolgus Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (C-Fc)
- 序列
- Phe20-Thr263
- 产品特性
- Recombinant Cynomolgus Sialic Acid-binding Ig-like lectin 15 is produced by our Mammalian expression system and the target gene encoding Phe20-Thr263 is expressed with a Fc tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus Siglec-15-Fc(Cat#PKSQ050112) at 2μg/ml (100 μl/well) can bind Anti-Human Siglec15 mAb. The ED50 of Anti-Human Siglec15 mAb is 20.9 ng/ml.
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- Discover our top product SIGLEC15 蛋白
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Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 60-322) protein (His-Avi Tag)
SIGLEC15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) protein (His-Avi Tag)SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 60-322) protein (His-Avi Tag,Biotin)SIGLEC15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 24-260) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (mFc Tag)SIGLEC15 宿主: 人 宿主: 人细胞 Recombinant >90 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 宿主: Cynomolgus 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (His tag)SIGLEC15 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (Active) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) (Active) protein (Fc Tag)SIGLEC15 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15) (AA 20-263) (Active) protein (Fc Tag)SIGLEC15 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCl, 100 mM Glycine, 150 mM NaCl, pH 7.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
- 别名
- Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33L3 (SIGLEC15 产品)
- 别名
- RGD1565948 Protein, CD33L3 Protein, HsT1361 Protein, SIGLEC-15 Protein, Cd33l3 Protein, EG620235 Protein, SIGLEC-I Protein, sialic acid binding Ig-like lectin 15 Protein, sialic acid binding Ig like lectin 15 Protein, Siglec15 Protein, SIGLEC15 Protein
- 背景
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Background: Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO--terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type Ig domains which have no binding activity. Siglecs differ in the number of these C2-type domains. Siglec-15 function is important for osteoclast formation and TRANCE/RANK Ligand signaling in osteoclasts.
Synonym: Sialic acid-binding Ig-like lectin 15, Siglec-15, CD33 antigen-like 3, CD33L3
- 分子量
- 53.1 kDa
- UniProt
- A0A2K5UY47
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