PD-1 Protein (AA 25-167) (His tag)
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- 抗原 See all PD-1 (PDCD1) 蛋白
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-167
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PD-1 protein is labelled with His tag.
- 原理
- Human PD-1/PDCD1 Protein
- 序列
- Leu25-Gln167
- 产品特性
- Recombinant Human PD-1/PDCD1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu25-Gln167.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human PD-1, His Tag at 0.5μg/ml (100μl/Well). Dose response curve for Anti-PD-1 Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product PDCD1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 别名
- PD-1 (PDCD1 产品)
- 别名
- CD279 Protein, PD-1 Protein, PD1 Protein, SLEB2 Protein, hPD-1 Protein, hPD-l Protein, Ly101 Protein, Pdc1 Protein, programmed cell death 1 Protein, PDCD1 Protein, Pdcd1 Protein
- 背景
- Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
- 分子量
- 17 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.
- 途径
- Cancer Immune Checkpoints
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